Items where Author is "Toso, Erik"
Bosnakovski, Darko and Kyba, Michael and Toso, Erik and da Silva, Meiri and Sunny, C. and Enner, Elizabeth and Yuan, C. and Walters, M. (2019) A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death. Science Advances.
Lee, JK and Bosnakovski, Darko and Toso, Erik and Dinh, T and Banerjee, S and Bohl, TE and Shi, K and Orellana, K and Kyba, Michael and Aihara, Hideki (2018) Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA. Cell Reports.
Bosnakovski, Darko and Gearhart , M and Toso, Erik and Ener, Elizabeth and Choi, Si Ho and Kyba, Michael (2018) Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression. Scientific Reports.
Bosnakovski, Darko and Toso, Erik and Hartweck, Lynn M. and Magli, Alessandro and Lee, HA and Thompson, ER and Dandapat, Abhijit and Perlingeiro, Rita C. R. and Kyba, Michael (2017) The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain. Journal of Cell Sciense.
Bosnakovski, Darko and Gearhart, Micah and Toso, Erik and Recht, Olivia and Cucak, Anja and Jain, Abhinav and Barton, Michelle and Kyba, Michael (2017) p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy. Disease Models & Mechanisms.
Choi, Si Ho and Bosnakovski, Darko and Strasser, JM and Toso, Erik and Walters, Michael and Kyba, Michael (2016) Transcriptional Inhibitors Identified in a 160,000-Compound Small-Molecule DUX4 Viability Screen. Slas Discovery: Advancing Life Sciences R&D, 21 (7). pp. 680-688. ISSN 2472-5560
Bosnakovski, Darko and Choi, Si Ho and Strasser, Jessica and Toso, Erik and Walters, Michael and Kyba, Michael (2014) High-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity. Skelet Muscle.